Site Administration The College of William and Mary

John D. Griffin, Ph.D.

Curriculum Vitae

Last Update: 01 June 2006

EDUCATION :

Ph.D. Physiology. The Ohio State University, Columbus. September, 1993.

M.S. Physiology. The Ohio State University, Columbus. January, 1991.

B.S. Biology (cum laude ). University of North Carolina at Wilmington. May, 1988.

 

ACADEMIC POSITIONS :

2004 - Present: Associate Professor, College of William and Mary (Tenured: 9/01/04 )

1999 - 2004: Assistant Professor, College of William and Mary

1996 - 1999: Assistant Professor, Sacred Heart University

1993 - 1996: Postdoctoral Research Fellow, Harvard Medical School

1993-1996: Teaching Fellow, Harvard University

 

HONORS:

1995: Certificate of Distinction in Teaching , Derek Bok Center for Teaching and Learning & Office of the Dean for Undergraduate Education, Teaching Fellow for Introductory Neurobiology , Department of Cellular and Molecular Biology, Harvard University

1994: Certificate of Distinction in Teaching , Derek Bok Center for Teaching & Office of the Dean for Undergraduate Education, Teaching Fellow for Introductory Neurobiology , Department of Cellular and Molecular Biology, Harvard University

1992: The Ohio State University , Bennett Graduate Research Society, Poster Presentation Award Winner

1990: Procter and Gamble Professional Opportunity Award, The Environmental and Exercise Physiology Section, FASEB Meetings

 

COURSES:

College of William and Mary

Neurobiology (BIOL 345), (Currenlty offered during the spring semester)

Neurophysiology (BIOL 447), (Currenlty offered during the fall semester)

Autonomic Nervous System (BIOL 676), Temperature Regulation (BIOL 404), Neurophysiology and its' Role in Body Systems Management (BIOL 504-07), Research in Biology (BIOL 403-26), Freshman Research (BIOL 201-26), Biology Writing (BIOL 300-26)

Sacred Heart University (1996-1999)

Neurobiology, Animal Physiology, Human Anatomy and Physiology, Introductory Concepts in Biology

Harvard University (1994 - 1996)

Introductory Neurobiology

 

FELLOWSHIPS AND GRANTS :

2006: Co- Principle Investigator for a National Insititutes of Health RO1 grant. Title: A multidisciplinary study of decision making across the adult lifespan: The effects of aging and neuropsychological functioning on behavior in economic experiments. In Review.

2005: Principle Investigator for a National Institute of Health R15 grant. Title: The responses of hypothalamic neurons to CGRP. 01/01/06 – 12/31/08 ($150,00)

2001: Recipient of a Teaching Career Enhancement Award from the American Physiological Society, for a proposal entitled: A Comprehensive Integration of Technology into the Teaching of Neurophysiology. $2,400

2000: Principle Investigator for a National Science Foundation CAREER award: The characterization of physiological responses and anatomical pathways involved in the generation of an immune response. $326,666 ( 8/17/00 - 8/16/05; IBN-9983624)

 

(While at Sacred Heart University )

1997: Principle Investigator for a MRI (Major Research Instrumentation) Grant Award from the National Science Foundation entitled: Acquisition of neurobiology equipment to characterize the physiological responses and anatomical pathways involved in the generation of a fever by hypothalamic thermoregulatory neurons. $95,000 ( 9/15/97 – 8/31/99; BES-9724544)

(While at Harvard University )

1993: National Research Service Award from the National Institute of Neurological Disorders and Stroke, entitled: Neurophysiological Generation of Fever. Two years of salary & benefits: $42,000 (11/93 - 11/95; NS09466)

(While at The Ohio State University )

1991: Neural Development, Plasticity, and Regeneration Training Grant: One year NIH funded Predoctoral Fellowship Award. One year of salary & benefits: $12,000 (06/91 - 06/92; NS07291)

 

RESEARCH PUBLICATIONS:

(William and Mary students are in Bold)

Fetsch, C.R., P.D. Heideman and J.D. Griffin. 2006. Effects of melatonin on thermally classified anterior hypothalamic neurons in the white-footed mouse ( Peromyscus leucopus ). Journal of Thermal Biology . (31) 40-49. (PDF)

Ranels, H.J. and J.D. Griffin. 2005. Effects of PGE 2 on the cellular properties of thermally classified neurons in the ventromedial preoptic area of the rat hypothalamus. BMC Neuroscience , 2005 6:14. (PDF)

Griffin , J.D. 2004. Central Thermosensitivity and the integrated responses of hypothalamic neurons. Journal of Thermal Biology . (29) 327-331. (PDF)

Griffin , J.D. 2003. Technology in the teaching of neuroscience: enhanced student learning. Advanced in Physiology Education. 27: 146-155. (PDF)

Griffin , J.D. 2003. Temperature Regulation and Fever. Encyclopedia of Neuroscience , 3rd Edition, Ed. Adleman, G. and Smith, B.H., Elsevier Sciecne B.V.

Ranels, H.J. and J.D. Griffin. 2003. The effects of prostaglandin E 2 on the firing rate activity of thermosensitive and temperature insensitive neurons in the ventromedial preoptic area of the rat hypothalamus. Brain Research . 964: 42-50. (PDF)

Griffin , J.D., C.B. Saper and Jack A. Boulant. 2001. Synaptic and morphological characteristics of temperature sensitive and insensitive hypothalamic neurons. Journal of Physiology ( London ) . 537: 521-535. (PDF)

Griffin , J.D. 1999. Temperature Regulation. Encyclopedia of Neuroscience , 2 nd Edition Ed. Adleman, G. and Smith, B.H., Elsevier Sciecne B.V., pages 2020-2021. (PDF)

Scammel, T.E., J.D. Griffin, J.K. Elmquist and C.B. Saper, 1998. Microinjection of cyclooxygenase inhibitor into the anteroventral preoptic region attenuates LPS fever. American Journal of Physiology . 274: R783-R789. (PDF)

Scammel, T.E., J.K. Elmquist, J.D. Griffin and C.B. Saper. 1996. Ventromedial preoptic Prostaglandin E2 activates fever-producing autonomic pathways. Journal of Neuroscience . 16(19):6246-6254. (PDF)

Boulant, J.A., A.R. Chow and J.D. Griffin. 1996. Determinants of hypothalamic neuronal thermosensitivity. Annals of the New York Academy of Sciences . 813: 133-138. (PDF)

Griffin , J.D., M.L. Kaple, A.R. Chow and J.A. Boulant. 1996. Cellular mechanisms for neuronal thermosensitivity in the rat hypothalamus. Journal of Physiology ( London ) 492: 231-242. (PDF)

Griffin , J.D. and J.A. Boulant. 1995. Temperature effects on membrane potential and input resistance in rat hypothalamic neurones. Journal of Physiology (London ) 488(2): 407-418. (PDF)

 

Articles Published in Non-Refereed Conference Proceedings:

Griffin , J.D. 2001. A Comprehensive Integration of Technology into the Teaching of Neurophysiology. Proceedings of the Syllabus 2001 Summer Conference.

Invited Scholarly Papers and Talks:

Distinguished Faculty Lecture . Faculty of Arts and Sciences, College of William and Mary. October 18, 2005 . “Thermoregulation, Fever & Hot Flashes…Oh My!”

Invited Session Speaker . XXXV International Congress of Physiological Sciences. April 5, 2005 . “Membrane mechanisms of thermosensitive neurons in the hypothalamus.”

Invited Opening Session Speaker . The First Integrated Meeting on the Thermal Physiology and Pharmacology of Thermoregulation. Rhodes , Greece . October 11, 2004 . “ Central Thermosensitivity and the Integrated Responses of Anterior Hypothalamic Neurons.”

Department of Biology, College of William and Mary. November 21, 2003 . “Thermoregulation, Fever & Hot Flashes…Oh My!”

The Harold L. Dorris Neurological Research Center , The Scripps Research Institute. April 17 th , 2003 . “Hypothalamic Control of Body Temperature and Fever.”

University of North Carolina at Wilmington . September 28, 2001 . "Hypothalamic Control of Thermoregulation."

 

Most Recent Presented Papers & Published Abstracts

Schaffer, B.E. and Griffin , J.D. Functional Identification of Thermally Classified Neurons in the Preoptic and Anterior Hypothalamus. American Physiological Society Annual Meeting, April 4 th, 2006.

Hack, L.M. and Griffin J.D. Effects of Leptin on the Firing Rates of Thermoregulatory Neurons in the Anterior Hypothalamus. American Physiological Society Annual Meeting, April 4 th , 2006.

Pecora, B.S. , Straub, A.L. and Griffin , J.D. Thermoregulatory Projections to the Dorsomedial Hypothalamus of the Rat. American Physiological Society Annual Meeting, April 4 th , 2006.

Fetsch, C.R. , Heideman, P.D. and Griffin , J.D. Effects of Melatonin on Thermoregulatory Hypothalamic Neurons in the White-Footed Mouse (Peromyscus Leucopus). Second International meeting on Physiology and Pharmacology of Temperature Regulation, March 4 th, 2006.

Braasch , D.C. and Griffin , J.D. The effects of Calcitonin Gene-Related peptide on the electrical Properties of Thermally Classified Neurons in the Anterior Hypothalamus of the Rat. Scholander Competition Session , XXXV International Congress of Physiological Sciences, April2 nd , 2005.

Deegan, E.M., Grimm, E.R. and Griffin , J.D. (2004) The Effects of Calcitonin Gene-Related Peptide on the Firing Rates of Thermosensitive and Temperature Insensitive Neurons in the Anterior Hypothalamus of the Rat. 2004 Experimental Biology meeting abstracts [on CD-ROM]. The FASEB Journal , 18, Abstract #704.20

Fetsch C.R. , P.D. Heideman and J.D. Griffin. (2003) Firing rate responses of thermally classified anterior hypothalamic neurons to melatonin in tissue slices from the white-footed mouse, Peromyscus leucopus . 2003 Experimental Biology meeting abstracts [on CD-ROM]. The FASEB Journal , 18, Abstract #63.2

Wright, J.L. and J.D. Griffin. (2003) The effects of leptin on the firing rates of thermosensitive and temperature-insensitive neurons in the anterior hypothalamus. 2003 Experimental Biology meeting abstracts [on CD-ROM]. The FASEB Journal , 18, Abstract #63.1

Thompson, E.D. and J.D. Griffin. (2003) The effects of cAMP dependent protein kinase activation on the firing rates of thermosensitive and temperature insensitive neurons in the ventromedial preoptic area of the rat hypothalamus. 2003 Experimental Biology meeting abstracts [on CD-ROM]. The FASEB Journal , 18, Abstract #64.4

Wallis, E.M. and J.D. Griffin. (2003) Morphological characterization of thermosensitive and temperature insensitive neurons in the ventromedial preoptic area of the rat hypothalamus. 2003 Experimental Biology meeting abstracts [on CD-ROM]. The FASEB Journal , 18, Abstract #64.5

Ranels, H.J. and J.D. Griffin. The effects of prostaglandin E2 on the cellular properties of thermally classified neurons in the ventromedial preoptic area of the rat hypothalamus. Featured Topic Session : Eicosanoids and Fever; Experimental Biology, Annual Meeting of the American Physiological Society, April 23, 2002.

Griffin , J.D. A comprehensive integration of computer technology into the teaching of neurophysiology. Computers in Research and Teaching Session ; Experimental Biology, Annual Meeting of the American Physiological Society, April 23, 2002.

Ranels, H.J . and J.D. Griffin. The effects of Prostaglandin E2 on the Firing Rate Responses of Thermorensitive and Insensitive Neurons in the Ventromedial Preoptic Area of the Hypothalamus. Society For Neuroscience, November 14, 2001.

Griffin , J.D. A Comprehensive Integration of Technology into the Teaching of Neurophysiology. Syllabus 2001 Summer Conference, July 23, 2001

 

Previous Presented Papers & Published Abstracts

Griffin , J.D. and C.B. Saper, 1996. The effects of IL-1beta and PGE 2 on hypothalamic thermosensitive and temperature insensitive neurons. FASEB Journal 10(3): A113.

Scammel, T.E., J.D. Griffin, J.K. Elmquist and C.B. Saper, 1996. Lipopolysacharide Fever requires the production of prostaglandins in the preoptic area of the hypothalamus. Soc. Neurosci. Abs. 22: 248.

Griffin , J.D. and C.B. Saper, 1996. The thermosensitivity of neurons in the ventromedial preoptic area of the hypothalamus. Neurosci. Abs. 22: 248.

Griffin , J.D., and C.B. Saper, 1995. Morphological characteristics of hypothalamic thermosensitive and temperature insensitive neurons. Soc. Neurosci. Abs. 21: 879.

West, A.E., C.C. Overly, K.E. Sorra, M.J. Belliveau, M.J. Bianchetta, J.M. Schwalb, J.D. Griffin, and J.E. Dowling. 1994. An interactive case method for teaching introductory neuroscience. Soc. Neurosci. Absts. 20: 208.

Griffin , J.D., and C.B. Saper. 1994. The effects of IL-1beta on the intracellular activity of hypothalamic thermosensitive and temperature insensitive neurons. Soc. Neurosci. Absts. 20: 1180.

Griffin , J.D., P. Wung Burgoon, and J.A. Boulant. 1993. Neuronal Thermosensitivity does not depend on thermal changes in resting membrane potential. FASEB Journal 7(3): A17.

Boulant, J.A. and J.D. Griffin. 1993. Determinants of thermosensitivity in hypothalamic neurons. page 9, In: Thermal Physiology 1993 , Absts of the Proceedings of the IUPS Thermal Physiology Commission Symposium , edited by A.S. Milton, Univ. of Aberdeen , Scotland .

Griffin , J.D. and J.A. Boulant. 1993. Mechanisms of hypothalamic neuronal warm sensitivity. Soc. Neurosci. Absts. 19:99.

Griffin , J.D. and J.A. Boulant. 1992. Hypothalamic warm sensitive neurons: Role of the temperature dependent pacemaker potential. FASEB Journal 6:A1198.

Griffin , J.D. and J.A. Boulant. 1992. Synaptic interactions of hypothalamic temperature sensitive and insensitive neurons. Soc. Neurosci. Absts. 18:877.

Griffin , J.D. and J.A. Boulant. 1991. Physiological and morphological characteristics of hypothalamic temperature sensitive neurons. FASEB Journal 5:A1400.

Griffin , J.D. and J.A. Boulant. 1991. Thermosensitive characteristics of hypothalamic neurons determined by whole-cell recording. Soc. Neurosci. Absts. 17:835.

Griffin , J.D., M.L. Kaple and J.A. Boulant. 1990. Hypothalamic regional differences in neuronal responses to temperature and cyclic AMP. Soc. Neurosci. Absts. 16:574.

Griffin , J.D., M.L. Kaple and J.A. Boulant. 1990. Cyclic AMP: a determinant of hypothalamic neuronal thermosensitivity. FASEB Journal 4:A720.

 

PROFESSIONAL SERVICE :

Director, Program in Neuroscience (2002 - Present)  

Borgenicht Advisory Board (2004 – Present)

IACUC Committee (2003 – Present)

 

University Invited Presentations & Courses

Admitted Student Lecture Series: April 17, 2006

Monroe Scholars Presentation (w/Guest Speaker: John Dowling, Harvard University ), William & Mary ( April 11, 2006 )

Monroe Scholars Presentation, William and Mary ( February 2, 2006 )

Admitted Student Lecture Series: April 25, 2005

Monroe Scholars Presentation, William and Mary ( October 25, 2004 )

Monroe Scholars Presentation, William and Mary ( April 11, 2000 )

Science Breakfast Conference Presentation, Sacred Heart University (April, 1998)

Invited Speaker, Connecticut Science Supervisors Association Annual Meeting (March, 1998)

Summer Technology Education Courses for High School Educators, Sacred Heart University "Smart" Center (1996 - 99)

 

Professional Society Memberships

Faculty for Undergraduate Neuroscience

Society for Neuroscience

American Physiological Society:

.................Environmental & Exercise Physiology Section

.................Teaching of Physiology Section: Chair, Awards & Events Committee (2005 - Present)

.................American Physiological Society, Perkins Fellowship Committee (2005 - Present)


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